Structured exercise program for older, sedentary adults is possible, safe and associated with benefits to physical and cognitive health.

Immobility in old age can lead to lower independence and quality of life and increased risk for falls and chronic disease. In the Lifestyle Interventions and Independence for Elders (LIFE) study, a large multicenter clinical trial, researchers found that a regular program of structured physical activity performed in the clinical setting could reduce mobility loss in older adults. Could this program work in a real-world environment?